Description
Product Characteristics:
The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. [provided by RefSeq].
Subcellular location: Secreted, Cell membrane
Synonyms: GM-CSF Receptor alpha, CD116, CD116 antigen, Colony Stimulating Factor 2 Receptor Alpha, Colony stimulating factor 2 receptor alpha chain, CSF 2R, CSF2RA, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GM CSF R alpha, GM CSF receptor alpha subunit, GMCSFR, GMR, Granulocyte Macrophage Colony Stimulating Factor Receptor Alpha Chain, GM-CSF-R-alpha, GMCSFR-alpha, GMR-alpha, CDw116, CSF2R_HUMAN, Granulocyte-macrophage colony-stimulating factor receptor subunit alpha.
Target Information: The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. [provided by RefSeq, Jul 2008]