Description
Product Characteristics:
Heterotrimeric guanine nucleotide-binding proteins (G proteins) transduce extracellular signals received by transmembrane receptors to effector proteins. Transducin is a guanine nucleotide-binding protein found specifically in rod outer segments, where it mediates activation by rhodopsin of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase. Transducin is also referred to as GMPase. GNGT1 encodes the gamma subunit of transducin (Hurley et al., 1984 [PubMed 6438626], Scherer et al., 1996 [PubMed 8661128]).[supplied by OMIM, Mar 2008].
Subcellular location: Cytoplasm, Cell membrane
Synonyms: G gamma 1, GNG1, GNGT1, Guanine nucleotide binding protein G, Transducin gamma chain, GBG1_HUMAN.
Target Information: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction