Description
Product Characteristics:
This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009].
Subcellular location: Secreted
Synonyms: Protein C, Anticoagulant protein C, Autoprothrombin IIA, Blood coagulation factor XIV, EC 3.4.21.69, PC, PROC, PROC1, Vitamin K dependent protein C precursor, APC, EC 3.4.21.69, PC, proC, PROC_HUMAN, Protein C inactivator of coagulation factors Va and VIIIa, Vitamin K dependent protein C, Vitamin K-dependent protein C, Vitamin K-dependent protein C light chain.
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