Description
Product Characteristics:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 5 (ZBTB5) is a 677 amino acid member of the Kr_ppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB5 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB5 functions as a transcription regulator.
Subcellular location: Nucleus
Synonyms: ZBTB 6, ZBTB6, ZBTB6_HUMAN, ZID, Zinc finger and BTB domain containing protein 6, Zinc finger and BTB domain-containing protein 6, Zinc finger protein 482, Zinc finger protein with interaction domain, ZNF 482, ZNF482.
Target Information: May be involved in transcriptional regulation