Description
Product Characteristics:
NEURL is involved in the determination of cell fate in the neurogenic region of the embryo and plays a role in the determination of cell fate in the central nervous system. NEURL may act as a tumor suppressor whose inactivation could be associated with malignant progression of astrocytic tumors.
Subcellular location: Cytoplasm, Cell membrane
Synonyms: h neu, h neuralized 1, Neuralized homolog, Neuralized like protein 1, NEURL1, RING finger protein 67, RNF67, NEU1A_HUMAN.
Target Information: Catalyzes the removal of sialic acid (N-acetylneuramic acid) moities from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage (By similarity)