Description
Product Characteristics:
Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas.
Subcellular location: Nucleus, Cell membrane
Synonyms: ALI1, DEGA, AMIGO-2, Amphoterin-induced protein 2, Alivin-1, Differentially expressed in gastric adenocarcinomas, AMIGO2
Target Information: Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain (By similarity)