Description
Product Characteristics:
MARCH6 (Membrane associated RING finger protein 6) belongs to the MARCH family, which contains at least seven membrane associated RING-CH (MARCH)proteins. MARCH proteins are E3 ubiquitin ligases and are located to subcellular membranes.
Synonyms: Doa10 homolog, E3 ubiquitin protein ligase MARCH6, MARCH 6, MARCH VI, MARCHVI, Membrane associated RING CH protein VI, Membrane associated ring finger C3HC4 6, Membrane associated RING finger protein 6, Protein TEB 4, Protein TEB4, RNF 176, RNF176, TEB 4, TEB4, RING finger protein 176, MARH6_HUMAN.
Target Information: This gene encodes a member of a family of membrane-associated E3 ubiquitin ligases containing RING-CH-type zinc finger motifs. Ubiquitination of type II deiodinase by the encoded protein is an important regulatory step in thyroid hormone signalling. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]