Description
Product Characteristics:
Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities.
Subcellular location: Cell membrane
Synonyms: NT, eN, NT5, NTE, eNT, CD73, E5NT, CALJA, 5'-nucleotidase, 5'-NT, Ecto-5'-nucleotidase, NT5E
Target Information: This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway. [provided by RefSeq, Sep 2008]