Description
Product Characteristics:
Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP (By similarity).
Subcellular location: Intracellular
Synonyms: A-kinase anchor protein 2, AKAP-2, AKAP-KL, Protein kinase A-anchoring protein 2, PRKA2, AKAP2, KIAA0920, PRKA2
Target Information: The protein encoded by this gene binds to the regulatory subunit of protein kinase A and is found associated with the actin cytoskeleton. The encoded protein mediates signals carried by cAMP and may be involved in creating polarity in certain signaling processes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]