Description
Product Characteristics: PDE1B has a preference for cGMP as a substrate. Synonyms: Polyclonal PDE1B antibody, Anti-PDE1B antibody, phosphodiesterase 1B, calmodulin-dependent antibody, PDE1B1 antibody, PDES1B antibody.
Target Information: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]