Description
Product Characteristics:
GLT8D1 is a 371 amino acid single-pass type II transmembrane protein that is expressed by a gene residing on human chromosome 3. Chromosome 3 is made up of about 214 million bases encoding over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. There are two isoforms of GLT8D1 that are produced as a result of alternative splicing events.
Synonyms: MGC94018, Da2 24, GALA4A, Glycosyltransferase 8 domain containing 1, Glycosyltransferase 8 domain-containing protein 1, Glycosyltransferase AD 017, MSTP139, GL8D1_HUMAN.
Target Information: This gene encodes a member of the glycosyltransferase family. The specific function of this protein has not been determined. Three alternatively spliced variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008]