Description
Product Characteristics:
Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation.
Synonyms: B144, D6S49E, Leucocyte specic transcript 1, Leukocyte-specic transcript 1 protein, Liver Specic Transporter, LST 1, Lst1, LST1_HUMAN, Lymphocyte antigen 117, MGC119006, MGC119007, Protein B144.
Target Information: The protein encoded by this gene is a membrane protein that can inhibit the proliferation of lymphocytes. Expression of this gene is enhanced by lipopolysaccharide, interferon-gamma, and bacteria. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]