Description
Product Characteristics:
May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin).
Subcellular location: Cell membrane
Synonyms: FPN1, HFE4, MTP1, IREG1, MST079, MSTP079, SLC11A3, Solute carrier family 40 member 1, Ferroportin-1, Iron-regulated transporter 1, SLC40A1
Target Information: The protein encoded by this gene is a cell membrane protein that may be involved in iron export from duodenal epithelial cells. Defects in this gene are a cause of hemochromatosis type 4 (HFE4). [provided by RefSeq, Jul 2008]