Description
Product Characteristics:
Reticulon 1A may be involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. It is expressed in neural and neuroendocrine tissues and cell cultures derived therefrom. Expression of isoform RTN1-C is strongly correlated with neuronal differentiation. Different isoforms have been described as a result of alternative splicing.
Subcellular location: Cytoplasm, Cell membrane
Synonyms: MGC133250, Neuroendocrine specic protein, NSP, Reticulon 1, Reticulon1, Reticulon1A, RTN 1, RTN1, RTN1 protein, RTN1_HUMAN.
Target Information: This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. This gene is considered to be a specific marker for neurological diseases and cancer, and is a potential molecular target for therapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011]