Description
Product Characteristics:
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the peptidyl glutamyl-like activity. May catalyze basal processing of intracellular antigens.
Synonyms: Delta, LMPY, Macropain delta chain, MGC5169, Multicatalytic endopeptidase complex delta chain, Proteasome prosome macropain subunit beta type 6, Proteasome beta 6 subunit, Proteasome catalytic subunit 1, Proteasome delta chain, Proteasome subunit beta 6, Proteasome subunit beta type 6, Proteasome subunit beta type-6, Proteasome subunit delta, Proteasome subunit Y, PSB6_HUMAN, PSMB 6, PSMB6, PSY large multunctional protease Y, Y antibody.
Target Information: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits\, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Jul 2008]