Description
Product Characteristics:
Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division.
Subcellular location: Nucleus
Synonyms: ALP, hALP, KIAA1709, N acetyltransferase 10, N acetyltransferase 10 GCN5 related, N acetyltransferase like, N acetyltransferase like protein, N-acetyltransferase 10, NAT10, NAT10_HUMAN, NET43.
Target Information: May have histone acetyltransferase (Potential)