Description
Product Characteristics:
MRas is a member of the RAS superfamily of GTP-binding proteins which are membrane-anchored, intracellular signal transducers responsible for a variety of normal cellular functions. They are oncogenically activated in a significant fraction of tumors. MRas participates in reorganisation of actin cytoskeleton. It is also involved in focal adhesion and can activate MAPK signalling.
Subcellular location: Cytoplasm, Cell membrane
Synonyms: muscle RAS oncogene homolog precursor, M ras, Muscle and microspikes Ras, Muscle Ras oncogene homologue, R ras3, R-ras3, Ras related protein MRas, Ras related protein RRas3, RRas3, XRas.
Target Information: This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]