Description
Product Characteristics:
May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.Contains a potential peptide which could stimulate a broad spectrum of phagocytotic cells.
Subcellular location: Secreted
Synonyms: ITIH, H1P, Inter alpha trypsin inhibitor heavy chain H1, Inter-alpha-inhibitor heavy chain 1, Inter-alpha-trypsin inhibitor complex component III, Inter-alpha-trypsin inhibitor heavy chain H1, ITI heavy chain H1, ITI-HC1, ITIH1, ITIH1_HUMAN, Serum-derived hyaluronan-associated protein, SHAP.
Target Information: The protein encoded by this gene is the heavy chain of a serine protease inhibitor that may serve to carry hyaluronan in plasma. This gene is part of a cluster of similar genes on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]