Description
Product Characteristics:
KCNC1 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. It forms a heteromultimer with KCNG3, KCNG4 and KCNV2.
Subcellular location: Cell membrane
Synonyms: C230009H10Rik, FLJ41162, FLJ42249, FLJ43491, Kcr2 1, KShIIIB, Kv3.1, Kv4, MGC129855, NGK2, Potassium voltage-gated channel subfamily C member 1, Shaw, Voltage gated potassium channel, KCNC1_HUMAN, Voltage gated potassium channel subunit Kv3.1, Voltage-gated potassium channel subunit Kv3.1.
Target Information: The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Multiple transcript variants encoding different isoforms have been inferred for this gene based on orthologous loci. [provided by RefSeq, Jul 2008]