Description
Product Characteristics:
Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways (By similarity).
Subcellular location: Cell membrane
Synonyms: NOK, SuRTK106, Tyrosine-protein kinase STYK1, Novel oncogene with kinase domain, Protein PK-unique, Serine/threonine/tyrosine kinase 1, STYK1
Target Information: Receptor protein tyrosine kinases, like STYK1, play important roles in diverse cellular and developmental processes, such as cell proliferation, differentiation, and survival (Liu et al., 2004 [PubMed 15150103]).[supplied by OMIM, Mar 2008]