Description
Product Characteristics:
ASNA1 is the human homolog of the E.coli arsA gene which is an ATPase, and is the catalytic component of a multisubunit oxyanion pump responsible for resistance to arsenicals and antimonials.
Subcellular location: Cytoplasm, Nucleus
Synonyms: ARSA 1, ARSA, ArsA arsenite transporter ATP binding homolog 1, ArsA arsenite transporter, ATP binding, E. coli, homolog of, 1, ArsA arsenite transporter, ATP-binding, homolog 1 bacterial, ARSA I, ARSA1, ARSAI, Arsenical pump driving ATPase, Arsenical resistance ATPase, Arsenite translocating ATPase, Arsenite transporting ATPase, Arsenite-stimulated ATPase, ASNA 1, ASNA I, Asna1 protein, ASNAI, ATPase Asna1, GET3, ASNA_HUMAN.
Target Information: This gene represents the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER). It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion. [provided by RefSeq, Oct 2011]