Description
Product Characteristics:
Highly expressed in spleen, lymph nodes, lung and placenta. Expressed at moderate level in thymus, kidney, heart and digestive tract. Weakly expressed in other lymphoid tissues.
Subcellular location: Cytoplasm
Synonyms: GIMA6_HUMAN, Gimap6, GTPase IMAP family member 6, hIAN2, hIAN6, Human immune associated nucleotide 2, IAN-2, IAN-6, IAN6, Immune associated nucleotide 2, Immune associated nucleotide 6, Immunity associated nucleotide 6 protein, Immunity-associated nucleotide 2 protein, Immunity-associated nucleotide 6 protein.
Target Information: This gene encodes a member of the GTPases of immunity-associated proteins (GIMAP) family. GIMAP proteins contain GTP-binding and coiled-coil motifs, and may play roles in the regulation of cell survival. Decreased expression of this gene may play a role in non-small cell lung cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is found in a cluster with seven additional GIMAP genes on the long arm of chromosome 7. [provided by RefSeq, Sep 2011]