Description
Product Characteristics:
Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.
Subcellular location: Cytoplasm
Synonyms: CERT, GPBP, CERTL, MRD34, STARD11, Collagen type IV alpha-3-binding protein, Ceramide transfer protein, hCERT, Goodpasture antigen-binding protein, START domain-containing protein 11, StAR-related lipid transfer protein 11, COL4A3BP
Target Information: This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]