Description
Product Characteristics:
This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].
Subcellular location: Cytoplasm
Synonyms: Cytoplasmic protein NCK2, NCK2, GRB4, Growth factor receptor bound protein 4, NCK adaptor protein 2, Nck-2, NCK2, NCK2_HUMAN, NCKbeta, Non-catalytic region of tyrosine kinase adaptor protein 2, Noncatalytic region of tyrosine kinase beta, SH2/SH3 adaptor protein NCK-beta, SH2/SH3 adaptor protein NCK-beta.
Target Information: This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]