Description
Product Characteristics:
May participate in the recruitment of inflammatory cells by injured or infected tissue. GCP-2(1-78) and, more potent, GCP-2(9-78) attract neutrophils and are involved in neutrophil activation.
Subcellular location: Secreted
Synonyms: LIX, GCP-2, Scyb5, Scyb6, ENA-78, AMCF-II, C-X-C motif chemokine 5, Cytokine LIX, Small-inducible cytokine B5, Cxcl5
Target Information: The protein encoded by this gene is an inflammatory chemokine that belongs to the CXC chemokine family. This chemokine is produced concomitantly with interleukin-8 (IL8) in response to stimulation with either interleukin-1 (IL1) or tumor necrosis factor-alpha (TNFA). This chemokine is a potent chemotaxin involved in neutrophil activation. [provided by RefSeq, Jul 2008]