Description
Product Characteristics:
This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB.
Subcellular location: Cytoplasm, Nucleus
Synonyms: CARD 6, CARD containing inhibitor of Nod1 and Cardiak-induced NF kB activation, CARD6, CARD6_HUMAN, Caspase recruitment domain family, member 6, Caspase recruitment domain protein 6, Caspase recruitment domain-containing protein 6, CINCIN1, D730008L15.
Target Information: This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB. [provided by RefSeq, Jul 2008]