Description
Product Characteristics:
E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis.Tissue specificity: Highly expressed in heart. Detected at intermediate levels in liver and kidney, and at low levels in placenta, brain and lung.
Subcellular location: Nucleus
Synonyms: C14orf18, CCNB1IP1, Chromosome 14 open reading frame 18, CIP1_HUMAN, Cyclin B1 interacting protein 1, Cyclin-B1-interacting protein 1, E3 ubiquitin-protein ligase CCNB1IP1, Enhancer of invasion 10, HEI10, Human enhancer of invasion 10.
Target Information: HEI10 is a member of the E3 ubiquitin ligase family and functions in progression of the cell cycle through G(2)/M.[supplied by OMIM, Apr 2004]