Description
Product Characteristics:
Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
Subcellular location: Cytoplasm, Cell membrane
Synonyms: DADR, DRD1A, D(1A) dopamine receptor, Dopamine D1 receptor, DRD1
Target Information: This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]