Description
Product Characteristics:
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
Subcellular location: Cytoplasm
Synonyms: HSP84, HSPC2, HSPCB, D6S182, HSP9B, Heat shock protein HSP 9-beta, HSP 9, Heat shock 84 kDa, HSP 84, HSP9AB1
Target Information: This gene encodes a member of the heat shock protein 90 family\, these proteins are involved in signal transduction, protein folding and degradation and morphological evolution. This gene encodes the constitutive form of the cytosolic 90 kDa heat-shock protein and is thought to play a role in gastric apoptosis and inflammation. Alternative splicing results in multiple transcript variants. Pseudogenes have been identified on multiple chromosomes. [provided by RefSeq, Dec 2012]