Description
Product Characteristics:
Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity.
Subcellular location: Cytoplasm, Nucleus
Synonyms: CGI17, pelo, PELO_HUMAN, pelota Drosophila homolog, pelota homolog, PRO1770, Protein pelota homolog.
Target Information: This gene encodes a protein which contains a conserved nuclear localization signal. The encoded protein may have a role in spermatogenesis, cell cycle control, and in meiotic cell division. [provided by RefSeq, Jul 2008]