Description
Product Characteristics:
Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion.
Subcellular location: Cytoplasm, Secreted
Synonyms: VG5Q, GPATC7, GPATCH7, HSU84971, HUS84971, Angiogenic factor with G patch and FHA domains 1, Angiogenic factor VG5Q, hVG5Q, G patch domain-containing protein 7, Vasculogenesis gene on 5q protein, AGGF1
Target Information: This gene encodes an angiogenic factor that promotes proliferation of endothelial cells. Mutations in this gene are associated with a susceptibility to Klippel-Trenaunay syndrome. Pseudogenes of this gene are found on chromosomes 3, 4, 10 and 16.[provided by RefSeq, Sep 2010]