Description
Product Characteristics:
This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.[provided by RefSeq, Feb 2011].
Subcellular location: Cytoplasm
Synonyms: epidermal, Fatty Acid Binding Protein 5, CFABP, Cutaneous fatty acid binding protein, DA11, Dferentiation associated lipid binding protein LP2, E-FABP, EFABP, Epidermal-type fatty acid-binding protein, FABP5, FABP5_HUMAN, Fatty acid binding protein epidermal, Fatty acid-binding protein 5, Fatty acid-binding protein, Keratinocyte lipid binding protein, PA-FABP, PAFABP, Psoriasis associated fatty acid binding protein homolog, Psoriasis-associated fatty acid-binding protein homolog.
Target Information: This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.[provided by RefSeq, Feb 2011]