Description
Product Characteristics:
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This gene is located on chromosome 13 within the minimal deletion region for B-cell chronic lymphocytic leukemia. Multiple alternatively spliced transcript variants have been found for this gene.
Subcellular location: Cytoplasm, Cell membrane
Synonyms: B cell chronic lymphocytic leukemia tumor suppressor Leu5, CAR, DLEU5, HGNC:9976, LEU5, Leukemia associated protein 5, Putative tumor suppressor RFP2, Ret finger protein 2, RING finger protein 77, RNF77, TRIM13, Tripartite mot protein 13, TRI13_HUMAN.
Target Information: This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This gene is located on chromosome 13 within the minimal deletion region for B-cell chronic lymphocytic leukemia. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]