Description
Product Characteristics:
VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder. PHM and PHV also cause vasodilation. PHM-27 is a potent agonist of the calcitonin receptor CALCR, with similar efficacy as calcitonin.
Subcellular location: Secreted
Synonyms: Vasoactive Intestinal peptide, MGC13587, Peptide histidine methioninamide 27, PHM 27, PHM27, PHV42, VIP peptides precursor, PHI, Peptide Histidine Isoleucine, Vasoactive intestinal peptide.
Target Information: The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]