Description
Product Characteristics:
Possible involvement in extravasation of leukocytes.
Subcellular location: Cell membrane
Synonyms: MS2, CD156, CD156a, Disintegrin and metalloproteinase domain-containing protein 8, ADAM 8, Cell surface antigen MS2, ADAM8
Target Information: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2009]