Description
Product Characteristics:
Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses (By similarity).
Subcellular location: Cytoplasm, Cell membrane
Synonyms: NL1, Neuroligin-1, NLGN1, KIAA1070
Target Information: transmembrane ligand for neurexins\, involved in development and maturation of synaptic connections [RGD, Feb 2006]