Description
Product Characteristics:
SLC29A4 (Solute carrier family 29 (nucleoside transporters), member 4) is involved in the re-uptake of monoamines into presynaptic neurons, thus determining the intensity and duration of monoamine neural signaling. It transports serotonin, dopamine and the neurotoxin 1-methyl-4-phenylpyridinium. It may also contribute to the regulation of extracellular adenosine concentrations.
Subcellular location: Cell membrane
Synonyms: SLC29A4phospho Y198, Brain transport protein PMAT, ENT 4, ENT4, Equilibrative nucleoside transporter 4, FLJ34923, S29A4_HUMAN, Plasma membrane monoamine transporter, PMAT, Solute carrier family 29 nucleoside transporters member 4, Solute carrier family 29 member 4.
Target Information: This gene is a member of the SLC29 family and encodes a plasma membrane protein with 11 transmembrane helices. This protein catalyzes the reuptake of monoamines into presynaptic neurons, thus determining the intensity and duration of monoamine neural signaling. It has been shown to transport several compounds, including serotonin, dopamine, and the neurotoxin 1-methyl-4-phenylpyridinium. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq, Jul 2008]