Description
Product Characteristics:
In addition to its role as a proinflammatory cytokine, may participate in T-cell effector function and perhaps T-cell development.
Subcellular location: Secreted
Synonyms: C7, IP10, CRG-2, INP1, IP-10, Ifi1, mob-1, Scyb1, gIP-1, C-X-C motif chemokine 1, 1 kDa interferon gamma-induced protein, Gamma-IP1, Interferon-gamma induced protein CRG-2, Small-inducible cytokine B1, Cxcl1, Crg2
Target Information: This gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. [provided by RefSeq, Jul 2008]