Description
Product Characteristics:
Involved in cytokinesis and septation where it has a role in the localization of F-actin.Tissue specificity: Ubiquitously expressed except in brain.
Subcellular location: Cytoplasm
Synonyms: bin3, BIN3_HUMAN, Bridging integrator 3, MGC14978.
Target Information: The product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes. [provided by RefSeq, Jul 2008]