Description
Product Characteristics:
May be a transcription factor required for the apoptosis response following survival factor withdrawal from myeloid cells. Might also have a role in the development and maturation of lymphoid cells.
Subcellular location: Cytoplasm, Nucleus
Synonyms: zinc and double PHD fingers family 2, Apoptosis response zinc finger protein, BAF45D antibody BRG1-associated factor 45D, D4 antibody D4 zinc and double PHD fingers family 2, DPF 2, DPF2, MGC10180, Protein requiem, REQ, REQU_HUMAN, Requiem, Requiem apoptosis response zinc finger, UBI D4, UBID 4, UBID4, Zinc finger protein ubi d4, Zinc finger protein ubi-d4.
Target Information: The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors. [provided by RefSeq, Jul 2008]