Description
Product Characteristics:
Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
Subcellular location: Cytoplasm, Cell membrane
Synonyms: RAI, NSHC, SHCC, N-Shc, SHC-transforming protein 3, Neuronal Shc, Protein Rai, SHC-transforming protein C, Src homology 2 domain-containing-transforming protein C3, SH2 domain protein C3, SHC3
Target Information: may be involved in brain-derived neurotrophic factor signalling during retinal development [RGD, Feb 2006]