Description
Product Characteristics:
PSA, prostate specific antigen, is the classic indicator for transformed pro-state tissue, however, in addition to being upregulated in prostate cancer, PSA is also upregulated in non-malignant conditions, such as benign prostatic hyperplasia. Prostein, also designated Prostate cancer-associated protein 6, is a prostate-specific, 553 amino acid transmembrane protein that is upregulated by androgens. It is considered a marker for prostate cells since it is expressed in all prostatic glandular cells as well as in normal and cancerous prostate tissues. Since it is able to elicit a tumor-directed cytotoxic T cell response, Prostein may be used as a target for the development of PSA- and T cell-based therapeutic strategies for prostate cancer.
Subcellular location: Cell membrane
Synonyms: IPCA 2, IPCA 8, IPCA6, PCANAP2, PCANAP6, PCANAP8, Prostate cancer associated gene 2, Prostate cancer associated gene 6, Prostate cancer associated gene 8, Prostate cancer associated protein 2, Prostate cancer associated protein 6, Prostate cancer associated protein 8, Prostate cancer-associated protein 6, Prostein, PRST, S45A3_HUMAN, Slc45a3, Solute carrier family 45 member 3.
Target Information: Please see product details or send an inquiry to antibodies-online for additional target information