Description
Product Characteristics:
Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.
Subcellular location: Cytoplasm, Cell membrane
Synonyms: LAMPB, CD107b, LAMP-2, LGP110, Lysosome-associated membrane glycoprotein 2, Lysosome-associated membrane protein 2, CD107 antigen-like family member B, LAMP2
Target Information: The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2008]