Description
Product Characteristics:
ASAP3 is a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion.
Subcellular location: Cytoplasm
Synonyms: ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 1, ACAP4, Arf GAP with SH3 domain, Arf GAP with SH3 domain, ANK repeat and PH domain containing protein 3, ARF6 GTPase activating protein, ArfGAP with SH3 domain, ankyrin repeat and PH domain, Centaurin, beta 6, CENTB6, DDEFL1, Development and dferentiation enhancing factor like 1, Up regulated in liver cancer 1 UPLC1, UPLC1.
Target Information: This gene encodes a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]