Description
Product Characteristics:
Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. The encoded protein, which may be a substrate of neuronal CDC2-like kinase, has also been found in vascular endothelial cells, where it mediates cell proliferation.
Subcellular location: Cytoplasm, Nucleus
Synonyms: C53, CDK5 activator binding protein C53, CDK5 regulatory subunit associated protein 3, HSF 27, HSF27, IC53, Ischemic heart CDK5 activator binding protein C53, LXXLL/leucine zipper containing ARFbinding protein, LZAP, MST016, OK/SW cl.114, PP1553, CK5P3_HUMAN.
Target Information: Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. The encoded protein, which may be a substrate of neuronal CDC2-like kinase, has also been found in vascular endothelial cells, where it mediates cell proliferation. [provided by RefSeq, Jul 2008]