Description
Product Characteristics:
GMCL1L has a possible function in spermatogenesis. It enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport. GMCL1L is also a probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Subcellular location: Nucleus
Synonyms: GCL, Germ cell less homolog 1 Drosophila like, Germ cell less protein like 1 like, GMCL 2, GMCL2, GMCLL_HUMAN.
Target Information: Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport. Probable substrate- specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity)