Description
Product Characteristics:
Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.
Subcellular location: Cell membrane
Synonyms: BLT2, NOP9, BLTR2, JULF2, KPG_004, LTB4-R2, LTB4-R 2, Leukotriene B4 receptor 2, LTB4 receptor JULF2, Leukotriene B4 receptor BLT2, Seven transmembrane receptor BLTR2, LTB4R2, BLT2R
Target Information: mouse homolog is a chemoattractant for myeloid leukocytes