Description
Product Characteristics:
MAVS (Mitochondrial Antiviral Signaling) mediates the activation of NF-kappaB and IRF3 in response to antiviral infection. Silencing of MAVS expression permits derepression of viral replication, while over expression of MAVS boosts antiviral immunity.
Subcellular location: Cytoplasm
Synonyms: CARD adapter inducing interferon beta, Card, Interferon beta promoter stimulator protein 1, Interferon-beta promoter stimulator protein 1, Ips 1, Ips1, KIAA1271, Mitochondrial anti viral signaling protein, Mitochondrial Antiviral Signaling, Mitochondrial antiviral signaling protein, Putative NF kappa B activating protein 031N, Virus induced signaling adapter, DKFZp547C224, DKFZp666M015, FLJ27482, FLJ31698, FLJ35386, FLJ38051, CARD, FLJ41962, IPS-1, IPS1, MGC3260, VISA, MAVS_HUMAN.
Target Information: This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]