Description
Product Characteristics:
BTBD1 contains a proline-rich region and a BTB/POZ domain which are typically involved in protein-protein interactions. The C-terminus of BTBD1 binds topoisomerase I and BTBD1 also interacts with TRIM5 isoform Delta. BTBD1 localizes to cytoplasmic bodies and is essential for myogenic differentiation.
Subcellular location: Cytoplasm
Synonyms: BTB POZ domain containing 1, BTB domain containing 1, BTB/POZ domain containing protein 1, BTBD 1, C15orf1, HCV NS5A transactivated protein 8, Hepatitis C virus NS5A transactivated protein 8, NS5ATP8, BTBD1_HUMAN.
Target Information: The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]