Description
Product Characteristics:
Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3.
Subcellular location: Cytoplasm, Secreted
Synonyms: Ckb-6, MPIF2, MPIF-2, SCYA24, C-C motif chemokine 24, CK-beta-6, Eosinophil chemotactic protein 2, Eotaxin-2, Myeloid progenitor inhibitory factor 2, Small-inducible cytokine A24, CCL24
Target Information: This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. [provided by RefSeq, Jul 2008]